Status:
COMPLETED
The Function and Proteome Alteration of HDL Subclass After Aerobic Exercise
Lead Sponsor:
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Conditions:
Obesity
Eligibility:
MALE
18-30 years
Phase:
NA
Brief Summary
Obesity is one of the most important risk factors for cardiovascular disease (CVD). HDL protein composition can be altered without a change in cholesterol content. Alteration of the HDL proteome can r...
Detailed Description
The aim of present study is to test the effects of 12-week moderate aerobic exercise on the proteome and function alteration of HDL sub-fractions in male youth with abdominal obesity. Study participa...
Eligibility Criteria
Inclusion
- Inactive youth males with abdominal obesity: BMI\>28 (weight in kilograms divided by height in meters squared) and weight stable for 6 months, waist to height ratio was ≥0.5 and/or waist circumference was ≥102 centimetres between the ages of 18 and 30 years.
Exclusion
- Participants with cardiovascular disease, diabetes or other chronic diseases, treatment with any medications, and had surgical procedures within the last 6 months.
Key Trial Info
Start Date :
January 30 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 20 2020
Estimated Enrollment :
6 Patients enrolled
Trial Details
Trial ID
NCT04294238
Start Date
January 30 2018
End Date
February 20 2020
Last Update
March 4 2020
Active Locations (1)
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1
Sun Yat-sen Memorial Hospital of Sun Yat-sen University
Guangzhou, Guangdong, China