Status:
ACTIVE_NOT_RECRUITING
Total Joint Arthroplasty in a Pediatric Population
Lead Sponsor:
University of Colorado, Denver
Collaborating Sponsors:
National Cancer Institute (NCI)
Conditions:
Total Joint Arthroplasty
Eligibility:
All Genders
10-25 years
Brief Summary
The primary purpose of this study is to examine the functional ability and quality of life in those patients who received a total joint arthroplasty (TJA) for reasons other than having a solid tumor a...
Detailed Description
Patients who undergo a total knee arthroplasty (TKA) or total hip arthroplasty(THA) for non-solid tumor related reasons, are most often those children who developed osteonecrosis or avascular necrosis...
Eligibility Criteria
Inclusion
- Populations 1,2,3
- Age between 10 years and 25 years
- Undergoing or have undergone total joint arthroplasty at Children's Hospital Colorado for non-solid tumor related reasons
- Treated at Children's Hospital Colorado by Dr. Nathan Donaldson, DO or Dr. Steven Thorpe, MD or previously by Travis Heare, MD
Exclusion
- Populations 1,2,3
- Subjects and/or parents not capable of completing basic questionnaires in English (HRQL data will not be collected from non-English speaking subjects because we do not have access to versions of these questionnaires that have been validated in languages other than English. These patients may be included at a later date when validated questionnaires are available).
- Subjects who underwent hemiarthroplasties, failed rotationplasty to arthroplasty conversions, or joint arthroplasty directly related to a tumor at the location of the joint
- Subjects diagnosed with mucopolysaccharidoses (MPS), pseudorheumatoid chondrodysplasia, or diastrophic dwarfism
- Inclusion Criteria: Population 4
- Age between 10 years and 25 years
- Treated at Children's Hospital Colorado by Dr. Nathan Donaldson, DO, or Dr. Steven Thorpe, MD or previously by Travis Heare, MD
- Symptomatic joint pain treated non-invasively via lifestyle modifications, over the counter or prescription pain medication, nerve blocks or steroid injections, and/or physical therapy
- Symptomatic joint pain treated via core decompression surgery at Children's Hospital Colorado by Dr. Nathan Donaldson, DO, or Dr. Steven Thorpe, MD, or previously by Travis Heare, MD
Key Trial Info
Start Date :
June 3 2019
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
March 1 2061
Estimated Enrollment :
1000 Patients enrolled
Trial Details
Trial ID
NCT04294693
Start Date
June 3 2019
End Date
March 1 2061
Last Update
December 24 2025
Active Locations (1)
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1
Children's Hospital Colorado
Aurora, Colorado, United States, 80045