Status:
TERMINATED
Exercise Intolerance and Skeletal Muscle Bioenergetics in Children With Deep Venous Thrombosis
Lead Sponsor:
University of Texas Southwestern Medical Center
Conditions:
Deep Vein Thrombosis
Pulmonary Embolism
Eligibility:
All Genders
8-21 years
Phase:
NA
Brief Summary
This is a prospective cohort study of 30 patients who are 8-21 years of age with venous thromboembolism (VTE)- either lower extremity deep venous thrombosis (DVT) or pulmonary embolism (PE).
Detailed Description
Participants will be in three groups- those with lower extremity DVT, those with PE, or those with both lower extremity DVT and PE. Patients will have blood drawn for thrombin generation assay, thromb...
Eligibility Criteria
Inclusion
- Age 8- ≤ 21 years old AND
- Lower extremity deep venous thrombosis OR
- Lower extremity deep venous thrombosis AND pulmonary embolism OR
- Pulmonary Embolism
Exclusion
- Contraindications to exercise, such as post-surgical patients with cast immobility or fractures
- Patients unable to follow instructions/commands at baseline due to developmental delay
- Patients with congenital heart disease and abnormal pulmonary circulation/perfusion
- Contraindications to undergoing magnetic resonance imaging
Key Trial Info
Start Date :
February 6 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 16 2022
Estimated Enrollment :
5 Patients enrolled
Trial Details
Trial ID
NCT04294849
Start Date
February 6 2020
End Date
February 16 2022
Last Update
November 15 2024
Active Locations (1)
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1
UT Southwestern Medical Center / Children's Medical Center
Dallas, Texas, United States, 75235