Status:
COMPLETED
Engaging Patients to Promote Deprescribing
Lead Sponsor:
VA Office of Research and Development
Conditions:
Medical Overuse
Inappropriate Prescribing
Eligibility:
All Genders
Phase:
NA
Brief Summary
One mechanism to reduce potentially inappropriate medications is through deprescribing, a deimplementation-based approach to thoughtfully discontinue a medication a patient is currently prescribed. Ma...
Detailed Description
Background - Despite multiple provider- and system-level interventions to reduce potentially inappropriate medications (PIMs), many Veterans are still prescribed drugs that provide little benefit, pla...
Eligibility Criteria
Inclusion
- Veteran with a Primary Care appointment at one of three Veteran Affairs Medical Centers (including Community Based Outpatient Clinics)
- PPI Cohort:
- \>90 consecutive days of PPI at any dose
- Diabetes Cohorts:
- HbA1c \<7%
- At least one of Age \>65 years
- Renal impairment
- Cognitive impairment
- either \>90 consecutive days insulin or sulfonylurea or \>90 consecutive days of \>2 DM medications (neither of which is insulin or sulfonylurea)
- Gaba Cohort:
- \>90 consecutive days with total daily dose \>1800mg
Exclusion
- PPI Cohort Exclusions:
- Diagnosis warranting PPI treatment
- Medication warranting PPI treatment
- Gaba Cohort Exclusions:
- Neuropathic pain
- Seizure disorder
- and/or Cancer-related pain
Key Trial Info
Start Date :
March 29 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 7 2023
Estimated Enrollment :
5946 Patients enrolled
Trial Details
Trial ID
NCT04294901
Start Date
March 29 2021
End Date
October 7 2023
Last Update
May 18 2025
Active Locations (4)
Enter a location and click search to find clinical trials sorted by distance.
1
San Francisco VA Medical Center, San Francisco, CA
San Francisco, California, United States, 94121
2
VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA
Boston, Massachusetts, United States, 02130
3
VA Central Western Massachusetts Healthcare System, Leeds, MA
Leeds, Massachusetts, United States, 01053-9764
4
James J. Peters VA Medical Center, Bronx, NY
The Bronx, New York, United States, 10468