Status:
COMPLETED
Extending CPAP Therapy in Stable Preterm Infants to Increase Lung Growth and Function
Lead Sponsor:
Cynthia McEvoy
Collaborating Sponsors:
Indiana University
National Heart, Lung, and Blood Institute (NHLBI)
Conditions:
Neonatal
Premature Birth
Eligibility:
All Genders
1-12 years
Phase:
NA
Brief Summary
This is a study to see if an extra 2 weeks of continuous positive airway pressure (CPAP) in stable preterm infants in the neonatal intensive care unit (NICU) can cause increased lung growth and lung f...
Detailed Description
This is a study to see if an extra 2 weeks of continuous positive airway pressure (CPAP) in stable preterm infants in the neonatal intensive care unit (NICU) can cause increased lung growth and lung f...
Eligibility Criteria
Inclusion
- Infants born at \>24 to ≤ 32 weeks gestation
- Treated with CPAP for ≥ 24 hours for respiratory distress (either as initial therapy or following extubation)
Exclusion
- Significant congenital heart disease
- Major malformations
- Chromosomal anomalies
- Culture proven sepsis at consent
- Complex maternal medical conditions
- Clinical instability
- Multiple gestations \> twins
- \<3rd or \>97th percentile for weight85
- Participating in another neonatal randomized clinical trial with a competing outcome
- Mother/legal guardian without stable method of communication
Key Trial Info
Start Date :
January 10 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 15 2024
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT04295564
Start Date
January 10 2020
End Date
March 15 2024
Last Update
August 17 2025
Active Locations (1)
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1
Doernbecher Neonatal Care Center at Oregon Health & Science University
Portland, Oregon, United States, 97239