Status:

TERMINATED

Impact of a Biofeedback Intervention on Microbiome, Metabolome, and Clinical Outcomes in Pediatric IBD (Study 2)

Lead Sponsor:

Nationwide Children's Hospital

Conditions:

IBD

Eligibility:

All Genders

8-17 years

Phase:

NA

Brief Summary

This prospective, randomized, longitudinal, controlled study will enroll pediatric CD patients with inflammatory, non-stricturing, and non-penetrating disease type with mild/quiescent disease based on...

Detailed Description

The inflammatory bowel diseases (IBD), which include Crohn's disease (CD) and ulcerative colitis (UC), affects 3 million Americans. In approximately 25-30% of patients, onset of these chronic diseases...

Eligibility Criteria

Inclusion

  • Age 8-17 years
  • Have inflammatory, non-stricturing, and non-penetrating CD with either mild/quiescent disease based on PCDAI or PGA
  • Live within a 2 hour drive of NCH

Exclusion

  • Participants are excluded if they have ulcerative colitis, penetrating and/or stricturing CD, have a comorbid chronic illness, perianal disease, taking antibiotics within the last 3 months, psychological disorders that they are undergoing treatment or taking medication for at that time, presence of a heart rhythm or other abnormality of heart rhythm on screening EKG, or undergoing psychological treatments such as cognitive behavioral therapy, mindfulness, or biofeedback therapy at the time of enrollment.
  • Age and language are limited by the demands of the study (questionnaire completion

Key Trial Info

Start Date :

March 12 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 14 2024

Estimated Enrollment :

48 Patients enrolled

Trial Details

Trial ID

NCT04296110

Start Date

March 12 2020

End Date

August 14 2024

Last Update

August 15 2024

Active Locations (1)

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Nationwide Childrens Hospital GI Clinic

Columbus, Ohio, United States, 43205