Status:
UNKNOWN
Corneal Biomechanical Changes of Allergic Conjunctivitis
Lead Sponsor:
Zhongshan Ophthalmic Center, Sun Yat-sen University
Conditions:
Conjunctivitis, Allergic
Keratoconus
Eligibility:
All Genders
7-50 years
Brief Summary
By measuring and comparing the corneal biomechanical parameters of normal people, patients with allergic conjunctivitis, keratoconus, whether allergic conjunctivitis causes changes in corneal biomecha...
Detailed Description
The current study involves 3 parts. The first part aims to explore whether allergic conjunctivitis causes changes in corneal biomechanics and to identify sensitive mechanical indicators of allergic co...
Eligibility Criteria
Inclusion
- Normal group
- No abnormalities are found by slit lamp and Pentacam.
- Diopters: diopter of spherical: -6.0D\~+3.0D, diopter of cylinder: -2.0D\~+2.0D, spherical equivalent: -6.0D\~+3.0D
- Best corrected visual acuity ≥ 1.0
Exclusion
- Patients diagnosed with other eye diseases other than refractive error.
- With a history of eye surgery or trauma.
- With systemic diseases such as immune diseases and connective tissue diseases.
- With a family history of keratoconus and glaucoma.
- Wear soft contact lens within 2 weeks or rigid contact lens within 1 month.
- SAC group
- Inclusion Criteria:
- Symptoms: Itching, foreign body sensation, increased discharge in conjunctival sac. And children may mainly show an increase in blinking frequency.
- Signs: conjunctival hyperemia, swelling, tarsal papillae.
- Medical history: seasonal onset
- Diopters: diopter of spherical: -6.0D\~+3.0D, diopter of cylinder: -2.0D\~+2.0D, spherical equivalent: -6.0D\~+3.0D
- Best corrected visual acuity ≥ 0.8
Key Trial Info
Start Date :
November 10 2019
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 30 2021
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT04299399
Start Date
November 10 2019
End Date
June 30 2021
Last Update
March 6 2020
Active Locations (1)
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1
Zhongshan Ophthalmic Center, Sun Yat-Sen University
Guangzhou, China, 510060