Status:
UNKNOWN
MicroRNA-150 and microRNA-155 in Multiple Sclerosis
Lead Sponsor:
Assiut University
Conditions:
Multiple Sclerosis
Eligibility:
All Genders
18-68 years
Brief Summary
A study To analyse the expression of circulating miR-150 and miR-155 in serum of MS patients, Evaluate the serum levels of oligoclonal bands, neurofilaments and chitinase-3-like-1 in serum of MS patie...
Detailed Description
Multiple sclerosis (MS) is a chronic neurodegenerative autoimmune disease characterized by infiltration of immune cells into the central nervous system (CNS) with subsequent demyelination, axonal dege...
Eligibility Criteria
Inclusion
- Patients diagnosed as MS (clinically and by imaging) according to revised 2017 McDonald Criteria .
- Each patient will be subjected to complete medical history uptake including : Age, Sex, age at onset of the disease, phenotype of the disease and its duration, frequency of relapses and remissions , EDSS(The Expanded Disability Status Scale ) is a method of quantifying disability in multiple sclerosis) and MRI findings.
Exclusion
- Patients with non neurological autoimmune diseases, malignancy, cardiac and renal diseases that can affect level of miRNAs .
Key Trial Info
Start Date :
April 1 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 1 2021
Estimated Enrollment :
140 Patients enrolled
Trial Details
Trial ID
NCT04300543
Start Date
April 1 2020
End Date
October 1 2021
Last Update
March 9 2020
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