Status:
UNKNOWN
A Cohort Study on Long-term Clinical Outcomes of Antiviral Therapy in Patients With Chronic Hepatitis B and Cirrhosis
Lead Sponsor:
Beijing Ditan Hospital
Conditions:
Chronic Hepatitis b
Eligibility:
All Genders
18-75 years
Brief Summary
This was a retrospective observational cohort study. The patients with chronic hepatitis B and cirrhosis who were treated with antiviral therapy in the Second Department of Liver Disease, Beijing Dita...
Detailed Description
This was a retrospective observational cohort study. The patients with chronic hepatitis B and cirrhosis who were treated with antiviral therapy in the Second Department of Liver Disease, Beijing Dita...
Eligibility Criteria
Inclusion
- Ages 18 to 75;
- Unlimited gender;
- Patients with chronic hepatitis B treated with interferon and / or nucleoside (acid) analogs (NA) antiviral therapy. All patients with chronic hepatitis B met the diagnostic criteria of the Chinese Guidelines for the Prevention and Treatment of Chronic Hepatitis B (2015)
- No hormones and / or immunosuppressants and other hepatoprotective drugs;
- Sign a written informed consent.
Exclusion
- Combined with other hepatitis virus (HCV, HDV) infections;
- Immune liver disease;
- HIV infection;
- long-term alcohol and / or other liver damage drugs;
- mental illness;
- Evidence of liver tumor (liver cancer or AFP\> 100 ng / ml);
- Decompensated cirrhosis;
- Those who have serious heart, brain, lung, kidney and other system diseases that cannot participate in long-term follow-up;
- There are hormones and / or immunosuppressants and other hepatoprotective drugs.
Key Trial Info
Start Date :
April 1 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
April 1 2021
Estimated Enrollment :
10000 Patients enrolled
Trial Details
Trial ID
NCT04301908
Start Date
April 1 2020
End Date
April 1 2021
Last Update
March 10 2020
Active Locations (1)
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1
Department of Hepatology Division 2, Beijing Ditan Hospital
Beijing, Beijing Municipality, China, 100015