Status:

RECRUITING

STRIVE Post-Market Registry Study

Lead Sponsor:

Olympus Corporation of the Americas

Conditions:

Emphysema

Eligibility:

All Genders

18+ years

Brief Summary

This is a single-arm, prospective, multi-center, Registry study to evaluate the long-term safety and effectiveness of the Spiration Valve System (SVS) for the treatment of severe emphysema in a post-m...

Detailed Description

This post-market study is a single-arm, prospective, multi-center Registry. It is designed to assess 36-month safety and effectiveness of this FDA approved product in a post-approval setting, and to s...

Eligibility Criteria

Inclusion

  • Adult patients with shortness of breath and hyperinflation associated with severe emphysema and evidence of low collateral ventilation.
  • Subjects must understand and voluntarily sign an informed consent form.

Exclusion

  • Subjects who are not appropriate for SVS therapy based upon the US FDA-approved IFU requirements.
  • Subjects who were withdrawn from this study for any reason will not be allowed to re-enroll.
  • Subjects who have incomplete screening or baseline data.

Key Trial Info

Start Date :

October 9 2021

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

April 1 2028

Estimated Enrollment :

150 Patients enrolled

Trial Details

Trial ID

NCT04302272

Start Date

October 9 2021

End Date

April 1 2028

Last Update

November 26 2025

Active Locations (13)

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Page 1 of 4 (13 locations)

1

Dignity Health St. Joseph's Hospital and Medical Center

Phoenix, Arizona, United States, 85013

2

El Camino, Taft Center for Clinical Research

Mountain View, California, United States, 94040

3

Northwestern University, Division of Pulmonary and Critical Care Medicine

Chicago, Illinois, United States, 60611

4

University of Chicago

Chicago, Illinois, United States, 60637