Status:

COMPLETED

The Effect of Gut Microbiota on Postoperative Liver Function Recovery in Patients With Hepatocellular Carcinoma

Lead Sponsor:

Tongji Hospital

Conditions:

Gut Microbiota

Hepatocellular Carcinoma

Eligibility:

All Genders

18-80 years

Brief Summary

The purpose of this study was to explore the correlation between postoperative recovery of liver function and gut microbiota in patients with hepatocellular carcinoma (HCC). Liver resection patients w...

Detailed Description

Primary hepatocellular carcinoma (HCC) is one of the most common malignant tumors in the world. At present, surgery is the first choice and the most effective way to treat it. Based on the case review...

Eligibility Criteria

Inclusion

  • The patient is diagnosed with liver cancer by b-mode ultrasonography before the surgery.
  • There is no antibiotic treatment, no severe diarrhea and regular diet within two weeks before the surgery.
  • It perform laparoscopic or open hepatectomy.
  • The postoperative pathological diagnosis is hepatocellular carcinoma.

Exclusion

  • No hepatectomy is performed during the operation.
  • The patient is't hepatocellular carcinoma due to the postoperative pathological diagnosis.
  • No stool samples are collected during the perioperative period.

Key Trial Info

Start Date :

October 1 2018

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 31 2020

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT04303286

Start Date

October 1 2018

End Date

December 31 2020

Last Update

May 12 2022

Active Locations (1)

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1

The hepatic surgery of Tongji hospital

Wuhan, Hubei, China, 430030