Status:
COMPLETED
24 Vs 48 Hours of Cefazolin or Cefuroxime as Prophylaxis
Lead Sponsor:
Saud Al Babtain Cardiac Center
Conditions:
Surgical Site Infection
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
A randomized control trial studying the effect of prophylactic antibiotics to reduce surgical site infections following cardiac surgery in adults using 1st generation cephalosporin (Cefazolin) or 2nd ...
Detailed Description
A prospective randomized controlled patient blinded study with 2x2 factional design. It aims to study optimal duration of antibiotic to reduce surgical site infections following cardiac surgery in adu...
Eligibility Criteria
Inclusion
- Ability to provide informed consent
- Planned to undergo a cardiac surgical procedure
Exclusion
- Patients on antibiotics on the day of surgery or those who received any within 7 days for any reason
- Patients taken to operating room as salvage
- Patients who are allergic to either cefuroxime or cefazolin
- Patients for LVAD or ECMO
- Patients who are known MRSA carriers
- Patients receiving steroid therapy
Key Trial Info
Start Date :
February 6 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 31 2022
Estimated Enrollment :
568 Patients enrolled
Trial Details
Trial ID
NCT04303390
Start Date
February 6 2018
End Date
May 31 2022
Last Update
April 11 2023
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Saud AlBabtain Cardiac Center
Dammam, Eastern Province, Saudi Arabia, 31463