Status:
COMPLETED
PRECISE: Pancreatic Cancer and Exercise
Lead Sponsor:
Queen's University, Belfast
Collaborating Sponsors:
Pancreatic Cancer UK
Belfast Health and Social Care Trust
Conditions:
Pancreas Adenocarcinoma
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The purpose of this study is to establish the feasibility of delivering a prescribed, individualised supervised aerobic and resistance exercise programme during adjuvant therapy, to improve survival a...
Detailed Description
Pancreatic ductal adenocarcinoma (PDAC) is the most common malignancy of the pancreas, representing 90% of all pancreatic neoplasms. The late presentation of symptoms and a lack of effective screening...
Eligibility Criteria
Inclusion
- age ≥ 18 years
- histologically proven pancreatic ductal adenocarcinoma
- complete macroscopic resection (R0 or R1 resection)
- patients recovering from surgery in time for chemotherapy to be delivered with adjuvant intent
- prior malignancy active within the previous 3 years other than locally curable cancers that have been apparently cured, such as basal or squamous cell skin cancer, superficial bladder cancer, or carcinoma in situ of the prostate, cervix, or breast
- Eastern Cooperative Oncology Group (ECOG) performance status 0-2
- deemed medically fit by treating team to participate in exercise programme
- able to provide informed consent.
Exclusion
- Macroscopically remaining tumour (R2 resection or tumour node metastasis (TNM) stage IV disease)
- Pre-existing cardiac conditions; Congestive heart failure or recent serious cardiovascular event
- Chest pain while undertaking physical activity
- Any related co-morbidities (diabetes; unstable angina; degenerative neuromuscular disease; mental health disorders; substance abuse)
Key Trial Info
Start Date :
August 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2022
Estimated Enrollment :
8 Patients enrolled
Trial Details
Trial ID
NCT04305067
Start Date
August 1 2020
End Date
August 1 2022
Last Update
February 16 2024
Active Locations (1)
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1
Belfast City Hospital
Belfast, United Kingdom, BT5 5JU