Status:

COMPLETED

Multiple Escalating Oral Doses Study of PF-07081532 in Adult Participants With Type 2 Diabetes Mellitus

Lead Sponsor:

Pfizer

Conditions:

Diabetes Mellitus Type 2

Eligibility:

All Genders

18-70 years

Phase:

PHASE1

Brief Summary

This is a randomized, placebo-controlled, double-blind (investigator- and participant-blinded), sponsor-open, dose-escalating study of PF-07081532 in patients with Type 2 diabetes on metformin (Parts ...

Eligibility Criteria

Inclusion

  • Key Inclusion Criteria for participants enrolling with T2DM:
  • Type 2 Diabetes treated with a stable dose of metformin at least 500 mg per day for at least 2 months prior to screening visit and use of no other medications for glycemic control.
  • HbA1c value between 7.0% and 10.5%, inclusive.
  • Key Exclusion Criterion for participants enrolling with T2DM:
  • Type 1 Diabetes or secondary forms of diabetes.
  • Key Inclusion Criterion for participants enrolling with obesity:
  • Obese (as indicated by screening BMI) non-diabetic adults.
  • Key Exclusion Criterion for participants enrolling with obesity:
  • -Type 1 or Type 2 Diabetes or secondary forms of diabetes.

Exclusion

    Key Trial Info

    Start Date :

    March 16 2020

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    July 14 2021

    Estimated Enrollment :

    66 Patients enrolled

    Trial Details

    Trial ID

    NCT04305587

    Start Date

    March 16 2020

    End Date

    July 14 2021

    Last Update

    February 5 2024

    Active Locations (2)

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    Page 1 of 1 (2 locations)

    1

    Anaheim Clinical Trials, LLC

    Anaheim, California, United States, 92801

    2

    Qps-Mra, Llc

    South Miami, Florida, United States, 33143

    Multiple Escalating Oral Doses Study of PF-07081532 in Adult Participants With Type 2 Diabetes Mellitus | DecenTrialz