Status:
ENROLLING_BY_INVITATION
Cytokine and Stress Hormone Responses to Exercise-induced Hypoxemia Among Endurance-trained
Lead Sponsor:
Gepner Yftach
Conditions:
Exercise-induced Arterial Hypoxemia
Eligibility:
All Genders
18-35 years
Brief Summary
It is well documented that exercise-induced arterial hypoxemia (EIAH) is highly prevalent among endurance-trained athletes performing heavy intensity exercise, regardless of sex and age. Although it h...
Detailed Description
Fifty highly trained endurance runners (men and women, age: 18-35 years) will be recruited for this study. The first testing session will serve as a screening tool to determine subject eligibility. Fo...
Eligibility Criteria
Inclusion
- 1\) Physically active (minimum of 50 km running/week) and maximal oxygen consumption \> 55 and 50 ml/kg-1/min-1 for men and women, respectively.
- 2\) classified as low risk based on a medical questionnaire, body mass index and non-smoking status.
- 3\) No history of pulmonary, metabolic and/or cardiovascular disease.
- 4\) normal pulmonary function as defined by a ≥ 80% of predicted forced vital capacity (FVC), forced expired volume in one second (FEV1) and FEV1/FVC according the American Thoracic Society standards.
Exclusion
- Smoking and/or any pulmonary, metabolic and/or cardiovascular disease.
- maximal oxygen consumption lower than set criteria.
Key Trial Info
Start Date :
March 1 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
September 1 2024
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT04305873
Start Date
March 1 2020
End Date
September 1 2024
Last Update
February 22 2024
Active Locations (1)
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1
Tel Aviv University
Tel Aviv, Israel