Status:
COMPLETED
Flow Controlled Ventilation in Cardiac Surgery
Lead Sponsor:
Medical University Innsbruck
Conditions:
Respiration; Artificial
Positive-Pressure Respiration
Eligibility:
All Genders
18-99 years
Phase:
NA
Brief Summary
This trial investigates effects of individualized (by compliance guided pressure settings) flow-controlled ventilation compared to best clinical practice pressure controlled ventilation in cardiac sur...
Detailed Description
The aim of the study is to investigate flow-controlled ventilation (FCV) during cardiac surgery requiring cardiopulmonary bypass. Previous preclinical trials have already shown improved oxygenation an...
Eligibility Criteria
Inclusion
- Male and female subjects \>18 years
- Body weight \>40 kg
- Elective cardiac surgery with CPB and without ventilation during CPB
- American Society of Anaesthesiologists (ASA) risc classification I-IV
- Written informed consent
Exclusion
- Emergency surgery
- Female subjects known to be pregnant
- Known participation in another interventional clinical trial
- High risk cardiac surgery such as double valve surgery, re-cardiac surgery, intraoperative cardiac arrest or pre-existing high grade cardiomyopathy (ejection fraction \<30%)
- Closing operation field without chest closure due to hemodynamic instability
- Acute endocarditis under antibiotic treatment
- Minimal invasive valve surgery via thoracotomy (MIC)
Key Trial Info
Start Date :
March 6 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 2 2021
Estimated Enrollment :
54 Patients enrolled
Trial Details
Trial ID
NCT04306757
Start Date
March 6 2020
End Date
March 2 2021
Last Update
March 23 2021
Active Locations (1)
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1
Medical University Innsbruck
Innsbruck, Tyrol, Austria, 6020