Status:
COMPLETED
Dexmedetomidine on Tourniquet Induced -Systemic Effects
Lead Sponsor:
Wonkwang University Hospital
Conditions:
Arthropathy of Knee
Spinal Anesthesia
Eligibility:
All Genders
20-80 years
Phase:
PHASE4
Brief Summary
Eighty patients were randomly assigned to either control (CON) or dexmedetomidine (DEX) group. DEX group received a loading dose of 0.5 µg/ kg of intravenous dexmedetomidine over 10 minutes, followed ...
Detailed Description
A total of 80 patients aged between 20 and 80 years, American Society of Anesthesiologists (ASA) physical status class I-III, who were scheduled to undergo elective TKA were enrolled in this study. Pa...
Eligibility Criteria
Inclusion
- patients aged between 20 and 80 years, American Society of Anesthesiologists (ASA) physical status class I-III, who were scheduled to undergo elective TKA
Exclusion
- Patients with history of rheumatoid arthritis, diabetes mellitus, hepatic or renal disease, allergy to drug being studied, heart block greater than first degree, left ventricle ejection fraction \< 55%, or chronic administration of anti-inflammatory drugs, or opioids were excluded. Patients with tourniquet times of less than 60 minutes or longer than 150 minutes or with conversion to general anesthesia during surgery
Key Trial Info
Start Date :
February 3 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 5 2020
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT04307290
Start Date
February 3 2020
End Date
March 5 2020
Last Update
March 13 2020
Active Locations (1)
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1
WonwangUH
Iksan, Jeollabuk-do, South Korea, 570-711