Status:

RECRUITING

CADASIL Registry Study

Lead Sponsor:

Bin Cai

Conditions:

Cadasil

Eligibility:

All Genders

18-85 years

Brief Summary

The aim of this study is to determine the clinical spectrum and natural progression of Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) and related ...

Eligibility Criteria

Inclusion

  • Sign informed consent.
  • Age\>18
  • Clinical diagnosis of patients with CADASIL,and confirmed by genetic test or skin biopsy
  • Asymptomatic NOTCH3 mutation carriers
  • Relatives of CADASIL patients or carriers
  • Unrelated healthy controls

Exclusion

  • Unable to cooperate with inspectors
  • Serious systemic illness, such as heart, liver, kidney disease or major mental illness
  • Contraindications for imaging examination

Key Trial Info

Start Date :

March 9 2020

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

March 9 2049

Estimated Enrollment :

1000 Patients enrolled

Trial Details

Trial ID

NCT04310098

Start Date

March 9 2020

End Date

March 9 2049

Last Update

September 28 2023

Active Locations (1)

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1

Department of Neurology , First Affiliated Hospital Fujian Medical University

Fuzhou, Fujian, China, 350004