Status:

UNKNOWN

Exposure to CARDIovascular Risk Assessed by Cardiac Adiposity in oBese adOlescents Eligible to a Residential Long-term Lifestyle Intervention by Diet and eXercise (CARDIBOX)

Lead Sponsor:

University Hospital, Clermont-Ferrand

Collaborating Sponsors:

Université d'Auvergne

LaPSCo laboratory, Physiological and Psychosocial Stress, UMR CNRS 6024, Clermont-Ferrand, France

Conditions:

Obesity

Adolescent Obesity

Eligibility:

All Genders

12-16 years

Phase:

NA

Brief Summary

The high prevalence of childhood obesity is a major public health issue, worldwide. Childhood obesity is associated with a high risk of cardiovascular events in adulthood, but recent studies also poin...

Detailed Description

The investigators aim to improve knowledge of the association between epicardial adipose tissue, myocardial lipid content, and left ventricular regional myocardial function. In this protocol, obese a...

Eligibility Criteria

Inclusion

  • age between 12 and 16 years old
  • mature (menarche)
  • suitable for physical activity
  • able to give an informative consent
  • affiliated at French insurance company
  • consent from the legal representatives
  • For obese adolescents: BMI greater than the 97th percentile of national curves.
  • For the control group: to be normal-weighted (no obesity if overweight, \<85th percentile of national curves).

Exclusion

  • Medical or surgical history judged by the investigator as incompatible with the study
  • Drugs that may interfere with the study results
  • Cardiovascular, hepatic, psychiatric, renal, or endocrinological diseases
  • Smoking
  • Alcohol consumption
  • Intense physical activity in competition

Key Trial Info

Start Date :

September 1 2020

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 1 2021

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT04310371

Start Date

September 1 2020

End Date

June 1 2021

Last Update

March 17 2020

Active Locations (1)

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CHU de Clermont-Ferrand

Clermont-Ferrand, France, 63000