Status:

UNKNOWN

Mucus Solids Concentration in Patients With Bronchiectasis

Lead Sponsor:

Universidad San Jorge

Collaborating Sponsors:

Hospital Clinic of Barcelona

Asociación Murciana de Fibrosis Quistica

Conditions:

Bronchiectasis

Eligibility:

All Genders

18+ years

Brief Summary

There is a need for biomarkers that can rapidly and sensitively detect therapeutic benefits of therapies designed to "rehydrate" airways and monitor disease severity and progression. In this study the...

Detailed Description

Prospective cross-sectional study of repeated measurements. The recruitment will be performed in 3 different cities of Spain: Zaragoza, Barcelona and Murcia. Subjects will be asked to repeatedly coll...

Eligibility Criteria

Inclusion

  • Confirmed diagnosis of CF (confirmed genetics) or diagnosis of non-CF bronchiectasis through high resolution computed tomography.
  • Aged ≥ 18 years.
  • Clinically stable at the time of recruitment.
  • Chronic sputum production (able to produce spontaneous sputum daily).
  • Current hypertonic saline user.
  • Able to provide written informed consent and perform the trial.

Exclusion

  • Current smoker or \>10 pack-year history of tobacco use.
  • Patient in transplantation or retransplantation list.

Key Trial Info

Start Date :

December 21 2020

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

August 1 2023

Estimated Enrollment :

36 Patients enrolled

Trial Details

Trial ID

NCT04310618

Start Date

December 21 2020

End Date

August 1 2023

Last Update

October 1 2021

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Marta San Miguel Pagola

Zaragoza, Aragon, Spain, 50014