Status:
RECRUITING
Autonomic Small Fiber Neuropathy and Ehlers Danlos Syndromes - Prospective Study and Registry
Lead Sponsor:
RWTH Aachen University
Collaborating Sponsors:
DLR German Aerospace Center
Conditions:
Autonomic Neuropathy
Ehlers-Danlos Syndrome Hypermobility Type
Eligibility:
All Genders
18-80 years
Brief Summary
We examine patients with different autonomic neuropathies and Ehlers Danlos syndromes compared to healthy controls at three different points over time (baseline, after 3 months and after 1.5 years) to...
Detailed Description
Inclusion of patients with autoimmune autonomic neuropathies/ pure autonomic failure, postural orthostatic tachycardia syndrome, small fiber neuropathies, Ehlers-Danlos syndromes, Mast cell activation...
Eligibility Criteria
Inclusion
- autonomic neuropathy
- Postural orthostatic tachycardia syndrome
- hypermobile or classical Ehlers Danlos syndromes
- Chronic fatigue syndrome, mast cell activation syndrome and/or PostCOVID
- healty controls
- between 18-80 years
- in patients: diagnosis and clinical testing in our outpatient clinic
- German speaking
Exclusion
- pregnancy
- Pacemaker or Deep brain Stimulation
- sensory or motor Polyneuropathy
- neurodegenerative disease
Key Trial Info
Start Date :
September 15 2019
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
September 15 2029
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT04310644
Start Date
September 15 2019
End Date
September 15 2029
Last Update
February 4 2025
Active Locations (1)
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1
University clinic RWTH Aachen
Aachen, North Rhine-Westphalia, Germany, 52074