Status:

COMPLETED

Effects of TIVA and Inhalation Anesthesia on Oxidative Stress Factors During Hypotensive Anesthesia

Lead Sponsor:

Bezmialem Vakif University

Conditions:

Oxidative Stress

Anesthesia

Eligibility:

All Genders

18-55 years

Phase:

NA

Brief Summary

Total intravenous anesthesia (TIVA) and inhalation anesthesia are two anesthesia methods that can be preferred for the maintenance of anesthesia. Sevoflurane and propofol are drugs used frequently in ...

Detailed Description

Controlled hypotension is defined as keeping systolic blood pressure in the range of 80-90 mmHg or mean arterial pressure in the range of 50-65 mmHg. Pharmacological and non-pharmacological methods ca...

Eligibility Criteria

Inclusion

  • Ages of 18-55
  • Who will undergo elective rhinoplasty
  • ASA Physical Status Classification System 1

Exclusion

  • Patients with a history of smoking,
  • Patients with a history alcohol use
  • Patients with a history drug use,
  • Body Mass Index (BMI)\>30
  • Patients with allergies to drugs to be used
  • Patients who refused to participate in the study Termination Criteria
  • Whose blood pressure values are out of the targets determined in 3 consecutive measurements

Key Trial Info

Start Date :

May 1 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 10 2021

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT04310748

Start Date

May 1 2020

End Date

January 10 2021

Last Update

November 15 2021

Active Locations (1)

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Bezmialem Vakif University

Fatih, Istanbul, Turkey (Türkiye), 34093