Status:
TERMINATED
Preoperative Detection of Lymph Node Metastases in Pancreatic and Periampullary Carcinoma Using USPIO MRI
Lead Sponsor:
Radboud University Medical Center
Conditions:
Pancreatic Cancer
Periampullary Cancer
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Adenocarcinoma's of the pancreas and periampullary region (distal bile duct, ampulla of Vater and duodenum) are cancers with a poor survival. Good preoperative TNM staging is important to determine th...
Detailed Description
Rationale: Pancreatic ductal adenocarcinoma (PDA) is a devastating disease with a dismal prognosis which has not improved substantially in the past 40 years. A good preoperative TNM staging is of imp...
Eligibility Criteria
Inclusion
- Age \> 18 years
- High index of suspicion of locally resectable or borderline resectable pancreatic or periampullary (= duodenal, papilla of Vater or distal bile duct) cancer
- Signed and dated informed consent
Exclusion
- Pregnancy
- Previous pancreatic surgery
- Previous treatment for the pancreatic or periampullary cancer
- Contraindications for 3T MRI
- Contraindications for USPIO based contrast agents (allergy, hereditary hemochromatosis, thalassemia, sickle cell anemia)
- Inability to provide informed consent
Key Trial Info
Start Date :
May 15 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2021
Estimated Enrollment :
26 Patients enrolled
Trial Details
Trial ID
NCT04311047
Start Date
May 15 2017
End Date
March 1 2021
Last Update
September 24 2021
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Radboudumc
Nijmegen, Netherlands, 6500