Status:

UNKNOWN

Concurrent Aerobic Exercise and Cognitive Training to Prevent Alzheimer's in At-risk Older Adults

Lead Sponsor:

Moai Technologies LLC

Collaborating Sponsors:

University of Minnesota

Conditions:

Mild Cognitive Impairment

Exercise Training

Eligibility:

All Genders

65+ years

Phase:

NA

Brief Summary

In this research, a unique "Exergame" has been developed and is being tested. The Exergame consists of unique Virtual Reality Cognitive Training (VRCT) games combined with concurrent cycling on a recu...

Detailed Description

A treatment that delays the onset of Alzheimer's disease (AD) by five years could be hugely cost-saving at an estimated $89 billion in 2030. However, nearly all (99.6%) drug trials for AD have failed,...

Eligibility Criteria

Inclusion

  • Cognitive complaint (defines as answering yes to the question "Do you feel that your memory or thinking skills have gotten worse recently within the last 2 years?");
  • Not engaging in aerobic exercise or cognitive training \>2 days/week, 30 minutes a session in the past 3 months;
  • Age 65 years and older;
  • Written consent.
  • Medical clearance to participate in a supervised exercise program

Exclusion

  • Resting heart rate \> 100 or \<50 beats/min with symptoms;
  • Dementia or mild cognitive impairment (self-report, diagnosis, or scoring \<26 on the Telephone Interview for Cognitive Status;
  • Evidence that cognitive decline or memory complaints were caused by underlying neurological or psychiatric disorder or chemical dependency as determined by primary health care provider;
  • Current enrollment in another intervention study;
  • ACSM contraindications to exercise or other factors that make exercise impossible or unsafe.

Key Trial Info

Start Date :

October 1 2019

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 1 2021

Estimated Enrollment :

96 Patients enrolled

Trial Details

Trial ID

NCT04311736

Start Date

October 1 2019

End Date

October 1 2021

Last Update

March 17 2020

Active Locations (1)

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Page 1 of 1 (1 locations)

1

University of Minnesota

Minneapolis, Minnesota, United States, 55455