Status:
RECRUITING
Combining MyoCI With Memory Reactivation to Improve Motor Recovery After Stroke
Lead Sponsor:
Northwestern University
Conditions:
Stroke
Eligibility:
All Genders
21-100 years
Phase:
NA
Brief Summary
This study will examine the combination of myoelectric computer interface (MyoCI) training with targeted memory reactivation (TMR) in chronic stroke survivors. The study aims to determine whether this...
Eligibility Criteria
Inclusion
- Age at enrollment is 21 or older
- Hemiparesis from first ever stroke affecting arm movement at least 6 months prior to screening
- Severe to moderate motor impairment (FMA-UE of 7-40)
- At least some voluntary shoulder and elbow muscle activation
Exclusion
- Inability to follow instructions of the MyoCI task
- Visual impairment (such as hemianopia) preventing full view of screen
- Anesthesia or neglect in the affected arm, or visual hemineglect (score of 2 on the NIH Stroke Scale Extinction and Inattention subtest)
- Participation in another study on the affected arm within 6 weeks of enrollment or any pharmacological study
- Inability to understand or follow commands in English due to aphasia or other reason
- Diffuse or multifocal infarcts in both hemispheres
- Substantial arm pain preventing participation for 90 minutes a day
- Spasticity treatment (pharmacological or Botox) within last 3 months
- Ferromagnetic implants that are MRI incompatible
Key Trial Info
Start Date :
February 25 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 30 2026
Estimated Enrollment :
70 Patients enrolled
Trial Details
Trial ID
NCT04312269
Start Date
February 25 2020
End Date
January 30 2026
Last Update
August 22 2025
Active Locations (1)
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1
Northwestern University
Chicago, Illinois, United States, 60611