Status:
UNKNOWN
Opioid-Sparing Protocol Comparing With Opioid-based Protocol After Bilateral Total Knee Arthroplasty
Lead Sponsor:
Taipei Veterans General Hospital, Taiwan
Conditions:
Knee Replacement
Postoperative Pain
Eligibility:
All Genders
20-90 years
Phase:
PHASE4
Brief Summary
The concern for the opioid use in the total knee arthroplasty continues to rise in recent decades. Historically, the total knee arthroplasty consumed high doses opioids in the postoperative periods. C...
Eligibility Criteria
Inclusion
- patient with bilateral advanced knee osteoarthritis undergoing simultaneous bilateral total knee arthroplasty surgery
- willing to participate in this study and randomly allocated to either opioid-sparing protocol or PCA protocol.
Exclusion
- patient who refused to participate or with contraindication or hypersensitivity to any of the study drugs
- chronic pain disorder (exceeding 50 mg oral morphine equivalence per day at time of recruitment)
- substance abuse (e.g. alcoholism)
- severe renal impairment.
Key Trial Info
Start Date :
March 20 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 20 2020
Estimated Enrollment :
56 Patients enrolled
Trial Details
Trial ID
NCT04314505
Start Date
March 20 2020
End Date
August 20 2020
Last Update
July 21 2020
Active Locations (1)
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1
Dep. of Orthopedics and Traumatology, Taipei Veterans General Hospital
Taipei City, Taipei, Taiwan, 112