Status:
UNKNOWN
Comparison of Hypertonic Saline and Mannitol on Brain Relaxation During Supratentorial Tumors Resection
Lead Sponsor:
Istanbul University
Conditions:
Brain Tumor - Metastatic
Brain Tumor, Adult: Glioblastoma
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
Hyperosmotic agents are used to decrease intracranial pressure. The aim of the study is to compare the effects of continuous 3% hypertonic saline (HS), bolus HS and 20% mannitol on intraoperative brai...
Detailed Description
After obtaining approval from the ethics committee and informed consent, a total of 90 patients aged 18-70 years, conscious (GCS\>13) and American Society of Anesthesiologists (ASA) class I-III, who h...
Eligibility Criteria
Inclusion
- Elective supratentorial tumor resection
- Glioblastoma multiforme
- Metastatic tumor
- Intracranial shift \>0.5 cm
- GCS\>13
Exclusion
- Renal failure
- Heart failure
- Electrolyte imbalance
Key Trial Info
Start Date :
April 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2022
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT04314674
Start Date
April 1 2020
End Date
December 1 2022
Last Update
March 19 2020
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