Status:

UNKNOWN

Optimised Lung Cancer Screening to Prevent Cardiovascular and Pulmonary Diseases Coupled With Primary Prevention

Lead Sponsor:

Istituto Clinico Humanitas

Collaborating Sponsors:

Ospedale San Raffaele

Conditions:

Lung Cancer

Cardiovascular Disease (CVD)

Eligibility:

All Genders

55+ years

Brief Summary

This project aims to implement a health prevention program for smokers or former smokers including early detection of lung cancer, cardiovascular disease (CVD) and chronic obstructive pulmonary diseas...

Eligibility Criteria

Inclusion

  • Age ≥ 55 years old and exposure to smoking more than 30 packs-year; which corresponds to 6-year risk of lung cancer, calculated according to the plco score (≥ 2%).
  • Smoker or former smoker Former smokers must have ceased smoking within the 15 years prior to enrollment in the study.
  • Absence of symptoms of lung cancer such as worsening of cough, hoarseness, hemoptysis and weight loss.

Exclusion

  • Previous diagnosis of lung cancer.
  • Positive extrapulmonary cancer history in the last 5 years (excluding in situ tumors or skin epidermoid tumor).
  • Performing a chest CT scan in the last 18 months.
  • Severe lung or extrapulmonary diseases that may preclude or invalidate appropriate therapy in case of diagnosis of malignant pulmonary neoplasia.

Key Trial Info

Start Date :

October 10 2018

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

October 1 2021

Estimated Enrollment :

2000 Patients enrolled

Trial Details

Trial ID

NCT04315766

Start Date

October 10 2018

End Date

October 1 2021

Last Update

March 20 2020

Active Locations (1)

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Istituto Clinico Humanitas

Rozzano, Milano, Italy, 20089