Status:

COMPLETED

Omidria and Dexycu, or Omidria and Dextenza Compared to Topical Prednisolone Acetate 1% Following Cataract Surgery

Lead Sponsor:

Silverstein Eye Centers

Collaborating Sponsors:

Ocular Therapeutix, Inc.

Conditions:

Cataract Surgery

Eligibility:

All Genders

Phase:

PHASE4

Brief Summary

This research will evaluate the efficacy of Omidria and Dexycu, Omidria and Dextenza, and Omidria and prednisolone acetate 1% in the resolution of post-operative inflammation and pain following catara...

Detailed Description

Prospective, randomized trial where patients will be randomly assigned to 1 of 3 groups, each with a sample size of 25 (total n=75). Group 1 will receive DEXYCU + Omidria (Omidria = ketorolac + phenyl...

Eligibility Criteria

Inclusion

  • Patients 18 years of age or older, undergoing routine, uncomplicated cataract surgery.

Exclusion

  • Any history of corneal dystrophy, corneal surgery within 6 months of cataract surgery, previous intraocular surgery, any concomitant eye drop use besides artificial tears, previous ocular trauma, or a history of treated glaucoma. No additional procedures can be done at the time of cataract surgery (e.g., stent placement, endo-laser, etc.), but femto-second laser-assisted surgery is permitted.

Key Trial Info

Start Date :

December 10 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 23 2020

Estimated Enrollment :

15 Patients enrolled

Trial Details

Trial ID

NCT04316936

Start Date

December 10 2019

End Date

December 23 2020

Last Update

June 15 2023

Active Locations (1)

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Silverstein Eye Centers

Kansas City, Missouri, United States, 64133