Status:

UNKNOWN

Burden of Staphylococcus Lugdunensis Infections in Hospitalized Patients

Lead Sponsor:

University Hospital, Rouen

Conditions:

Staphylococcus Lugdunensis Infection

Eligibility:

All Genders

18+ years

Brief Summary

Staphylococcus lugdunensis is a coagulase-negative Staphylococcus (CoNS) belonging to the normal human skin flora. It is responsible for a wide variety of infections, such as skin and soft tissue infe...

Eligibility Criteria

Inclusion

  • Age ≥ 18 years
  • Hospitalized patients
  • Patients with clinical criteria for infection
  • Patients with at least one of the following microbiological criteria for infection caused by S. lugdunensis, S. aureus or other CoNS species:
  • Pure culture in a normally sterile site excluding blood culture
  • At least two blood cultures or one blood culture positive and a context of endocarditis or colonized material (catheter, pace-maker…)
  • Pure or predominant positive culture (probable infection) in a superficial skin sample taken by swab
  • At least two surgical positive cultures in case of osteo-articular infection
  • Pure positive urine culture (≥104 CFU / mL), in association with abnormal leukocyturia (≥ 104 / mL)
  • Patients (or trusted person) who have read the information note and who do not oppose to research participation
  • Patient affiliated to the French Social Security system

Exclusion

  • Age \<18 years
  • Patient not affiliated to the French Social Security system
  • Patient with a positive culture for S. lugdunensis, S. aureus or other CoNS species but who does not meet the inclusion criteria defined above
  • Pulmonary infections of patients with cystic fibrosis
  • Patient already included in the study for an infection caused by S. lugdunensis, S. aureus or other CoNS species
  • Person deprived of their liberty by an administrative or judicial decision, person placed under the protection of justice, guardianship or curatorship.

Key Trial Info

Start Date :

September 1 2020

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2022

Estimated Enrollment :

300 Patients enrolled

Trial Details

Trial ID

NCT04318262

Start Date

September 1 2020

End Date

December 1 2022

Last Update

June 30 2020

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Caen University Hospital

Caen, France

2

Rouen University Hospital

Rouen, France