Status:

COMPLETED

A Novel Tapered Applicator for Vaginal Vault Brachytherapy

Lead Sponsor:

Yale University

Conditions:

Endometrial Cancer

Brachytherapy

Eligibility:

FEMALE

18+ years

Phase:

NA

Brief Summary

This study will assess the comfort and fit of a novel applicator for endometrial cancer patients who are candidates for vaginal brachytherapy. This study is only assessing the applicator fitting. No p...

Detailed Description

In the treatment of endometrial cancer, adjuvant vaginal brachytherapy is typically performed to deliver radiation dose to the apex of the vagina with a fixed diameter vaginal applicator which extends...

Eligibility Criteria

Inclusion

  • Eligibility Criteria
  • Patients with stage I-IV endometrial cancer.
  • Patient must have been treated with hysterectomy.
  • A radiation oncology determined the patient's disease warrants adjuvant treatment with vaginal brachytherapy as sole adjuvant radiotherapy.
  • Patient consented to receive standard of care vaginal brachytherapy treatment.
  • Vaginal cuff deemed healing appropriately by treating radiation oncologist during initial consultation without evidence of infection, pelvic symptoms, or other surgical complications.
  • 18 ≤ Age
  • English speaking.
  • Exclusion Criteria
  • Subjects meeting any of the criteria below may not participate in the study:
  • Requires premedication with pain medications and/or anxiolytics during applicator fitting.
  • Will receive pelvic EBRT.
  • Prior known diagnosis of lupus, scleroderma, dermatomyositis, Crohn's disease, ulcerative colitis, pacemakers, or other contraindications to radiotherapy.

Exclusion

    Key Trial Info

    Start Date :

    July 16 2020

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    March 20 2023

    Estimated Enrollment :

    21 Patients enrolled

    Trial Details

    Trial ID

    NCT04318340

    Start Date

    July 16 2020

    End Date

    March 20 2023

    Last Update

    July 14 2023

    Active Locations (1)

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    Page 1 of 1 (1 locations)

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    Smilow Cancer Hospital

    New Haven, Connecticut, United States, 06519