Status:

RECRUITING

Effect of Fermented Protaetia Brevitarsis Seulensis Powder on Alcohol-induced Liver Disease

Lead Sponsor:

Pusan National University Yangsan Hospital

Conditions:

Alcoholic Liver Disease

Eligibility:

All Genders

19+ years

Phase:

NA

Brief Summary

The investigators conduct a randomized, double-blind, placebo-controlled study to investigate the effects of Fermented Protaetia brevitarsis seulensis powder on Alcohol-induced Liver Disease in adults...

Detailed Description

Previous studies have indicated that Fermented Protaetia brevitarsis seulensis powder may have the ability to improve liver function in adults with alcohol-induced liver disease. Therefore, the invest...

Eligibility Criteria

Inclusion

  • Gamma-glutamyl transferase ranging from upper limit of reference to four times of upper limit

Exclusion

  • Abnormal liver or renal function (i.e., serum aminotransferase activity \> 3 times of upper limit of reference range and serum creatinine concentrations \> 1.2 mg/dL)
  • Diabetes (diagnosed clinically or fasting glucose level \> 126 mg/dL)
  • History of viral hepatitis or cancer
  • Uncontrolled hypertension
  • History of serious cardiac disease such as angina or myocardial infarction
  • History of gastrectomy
  • History of medication for psychiatric disease
  • Administration of oriental medicine including herbs within the past 4 weeks

Key Trial Info

Start Date :

January 1 2020

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2025

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT04320199

Start Date

January 1 2020

End Date

December 31 2025

Last Update

June 4 2025

Active Locations (1)

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Pusan National University Yangsan Hospital

Pusan, Ami-dong, South Korea, 602-739