Status:

RECRUITING

PANDA Gym: Automated Assessment of Neurodevelopment in Infants at Risk for Motor Disability

Lead Sponsor:

University of Pennsylvania

Collaborating Sponsors:

Children's Hospital of Philadelphia

Conditions:

Pediatric ALL

Infant Development

Eligibility:

All Genders

Up to 6 years

Brief Summary

Early childhood detection of motor delays or impairments provides the opportunity for early treatment which improves health outcomes. This study will use state of the art sensors combined with machine...

Detailed Description

For children with neurodevelopmental disabilities, early treatment in the first year of life improves long-term outcomes. However, the investigators are currently held back by inadequacies of availabl...

Eligibility Criteria

Inclusion

  • Infants, male and female, between 0-6 months (Infants older than 6 months before initial enrollment will be excluded).
  • Infants with early brain injury (EBI):
  • Hydrocephalus
  • Hypoxic-ischemic encephalopathy (HIE)
  • Periventricular leukomalacia (PVL)
  • Intraventricular hemorrhage (IVH)
  • Stroke
  • Healthy infants (controls):
  • o No history of early brain injury (EBI)
  • Infants without EBI/risk for future disability:
  • Infants without known brain injuries, but with a history of preterm birth less than 32-week gestation with significant medical problems, difficulty eating, or who lack head control at 4 months of age or later will be classified as moderate risk.

Exclusion

    Key Trial Info

    Start Date :

    November 1 2020

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ESTIMATED

    End Date :

    July 1 2026

    Estimated Enrollment :

    1700 Patients enrolled

    Trial Details

    Trial ID

    NCT04321200

    Start Date

    November 1 2020

    End Date

    July 1 2026

    Last Update

    September 23 2025

    Active Locations (1)

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    1

    Childrens Hospital of Philadelphia

    Philadelphia, Pennsylvania, United States, 19104