Status:

COMPLETED

Analysis of Competitive Posterior Cruciate Retaining (PCR) and Posterior Stabilized (PS) Total Knee Arthroplasty (TKA)

Lead Sponsor:

The University of Tennessee, Knoxville

Collaborating Sponsors:

Smith & Nephew, Inc.

Conditions:

Knee Osteoarthritis

Total Knee Arthroplasty

Eligibility:

All Genders

18-85 years

Brief Summary

The purpose of the study is to acquire kinematic in vivo fluoroscopy data from subjects who were implanted with Stryker Posterior Cruciate Retaining (PCR) , Stryker Posterior Stabilized (PS), Zimmer P...

Detailed Description

The objective for this study is to analyze the in vivo kinematics for subjects implanted with either a Stryker PCR, Stryker PS, Zimmer PCR, and Zimmer PS TKA and to compare those patterns to subjects ...

Eligibility Criteria

Inclusion

  • Subjects will have one of the following implant types: 1) Stryker Triathlon PCR TKA (28 subjects), 2) Stryker Triathlon PS TKA (28 subjects), 3) Zimmer Persona PCR TKA (28 subjects) and 4) Zimmer Persona PS TKA (28 subjects).
  • Patients must be at least three months post-operative.
  • Participants must not experience any pain or other post-operative complications.
  • Participants must have a stable TKA and be capable of performing a deep knee bend activity.
  • Participants must weigh less than 300 lbs., not underweight (BMI \< 18.5) or too obese (BMI\>35).
  • Must be in the age range of 18 years to 85 years (both inclusive).
  • Participants must be able to perform the required activities without concern.
  • Subjects must be willing to sign the Informed Consent (IC) form to participate in the study.
  • Patients who do not have previous surgery on the implanted knee that might restrict their movement.

Exclusion

  • Pregnant, potentially pregnant, lactating females or of childbearing age. To satisfy radiation protocol, each female subject will be asked if she is pregnant, or possibly could be pregnant. A pregnant person will not be allowed to participate in the study. (All potential female study patients will be asked if they are premenopausal or if they have undergone a hysterectomy. If the possibility of pregnancy exists, a pregnancy kit will be given to the patient at the informed consent meeting, just prior to the fluoro. Results of the test will be recorded in a test log. Any female patient showing a positive test will be excluded from testing.)
  • Subjects without the required type of knee implant.
  • Cannot have pain in other parts of the body that would prohibit the subject from performing the activities).
  • Cannot have ligamentous pain and/or laxity.
  • Unwilling to sign IC/HIPAA form(s).
  • Does not speak English.
  • Patients who have enrolled in a fluoroscopic kinematic study within the past year.
  • Patients currently involved in any personal injury litigation, medical/legal or worker's compensation claims.
  • Patients with known drug or alcohol abuse histories or psychological disorders that could affect ability to complete all aspects of the study.
  • Patients with neurological or musculoskeletal disorders that might adversely affect weight-bearing motion ability.

Key Trial Info

Start Date :

February 24 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

May 16 2022

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT04321356

Start Date

February 24 2020

End Date

May 16 2022

Last Update

November 28 2023

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Tennessee Orthopaedic Clinic

Knoxville, Tennessee, United States, 37923

2

The University of Tennessee

Knoxville, Tennessee, United States, 37996