Status:
COMPLETED
Safety and Efficacy of Hydroxychloroquine Associated With Azithromycin in SARS-Cov-2 Virus (COVID-19)
Lead Sponsor:
Hospital do Coracao
Collaborating Sponsors:
Hospital Israelita Albert Einstein
Hospital Sirio-Libanes
Conditions:
Coronavirus Infections
Eligibility:
All Genders
18+ years
Phase:
PHASE3
Brief Summary
Coronavirus (COVID-19) is a somewhat new and recognized infectious disease that is now spreading to several countries in the world, including Brazil. Hydroxychloroquine and azithromycin may be useful ...
Detailed Description
The current pandemic associated with coronavirus disease 2019 (COVID-19) represents a major global health challenge. There are no effective therapies for the management of COVID-19 that have been prov...
Eligibility Criteria
Inclusion
- Patients with suspected or confirmed COVID-19 admitted to inpatient units and intensive care units
Exclusion
- Need for oxygen supplementation \> 4 litters per min
- Patients using a high-flow nasal catheter
- Patients using non-invasive mechanical ventilation
- Patients using invasive mechanical ventilation
- Males and females aged \< 18 years
- Pregnancy
- Allergy to chloroquine or derivatives
- Allergy to azithromycin
- Patients that have already received more than one dose of either azithromycin or hydroxychloroquine before enrollment
- Patients with respiratory symptoms for more than 14 days
Key Trial Info
Start Date :
April 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 2 2020
Estimated Enrollment :
667 Patients enrolled
Trial Details
Trial ID
NCT04322123
Start Date
April 1 2020
End Date
June 2 2020
Last Update
April 5 2022
Active Locations (28)
Enter a location and click search to find clinical trials sorted by distance.
1
Hospital Maternidade São José - UNESC - Fundação Social Rural de Colatina
Colatina, Espírito Santo, Brazil
2
Hospital Geral Clériston Andrade
Feira de Santana, Estado de Bahia, Brazil
3
Hospital Ana Nery - HAN/SESAB
Salvador, Estado de Bahia, Brazil
4
HHospital SAMUR
Vitória da Conquista, Estado de Bahia, Brazil