Status:
WITHDRAWN
The DURATION Study: reDUcing sedentaRy behAviour to Maintain cogniTIve functiON.
Lead Sponsor:
Western University, Canada
Conditions:
Sedentary Behavior
Mild Cognitive Impairment
Eligibility:
All Genders
65+ years
Phase:
NA
Brief Summary
Rationale: Older adults spend the majority of their time in sedentary behaviours (SB). High amounts of SB have been correlated with reduced cognitive performance. Long periods of time spent sitting re...
Detailed Description
This study will be a randomized crossover trial and reported in accordance with CONSORT guidelines. The study will involve a total of three seven-day conditions (2 experimental and 1 control) with a t...
Eligibility Criteria
Inclusion
- Age ≥ 65 years
- Have a caregiver that works with you at least 20 hours a week (needs to be present for the familiarization session (explained below) and drop-off and pick-up from lab sessions)
- Diagnosis of diabetes by a healthcare provider (e.g. family doctor).
- Diagnosis of MCI by a healthcare provider
- Self-report being physically inactive (not meeting the current PA guidelines of 150 min MVPA/week)
- Self-report being sedentary- (defined as self-reported sedentary time ≥ 7 h/day)
- Able to walk one block without an assistive device
- Own a smartphone with unlimited outgoing text messages and access to internet connection. The smartphone must be either iphone 7 (with iOS of 12.2 or higher) or Android operating system 5 or higher to allow for Libre View mobile application compatibility.
- Able to read, write and understand English
Exclusion
- Currently smoke
- Depression (Geriatric Depression Score short-form \> 6 (GDS)) (Yesavage, Brink, Rose, \& et al, 1983).
- Medication: hypoglycemics; antilipidemics; antidepressants; beta blockers; anti-anxiety agents
- Peri-menopausal or menopausal women (must be post-menopausal)
- Excessive alcohol consumption (\> 8 points on the Alcohol Use Disorders Identification Test)
- Uncontrolled hypertension (measured systolic \> 140 mmHg or diastolic \> 90 mmHg)
Key Trial Info
Start Date :
December 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2025
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT04323423
Start Date
December 1 2025
End Date
December 1 2025
Last Update
March 5 2024
Active Locations (1)
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1
The University of Western Ontario
London, Ontario, Canada