Status:

TERMINATED

Comparison of Pulsed-field Gel Electrophoresis and Whole Genome Sequencing to Determine Transmission Rate of ESBL-producing E.Coli

Lead Sponsor:

University Hospital, Basel, Switzerland

Conditions:

Analysis Transmission Rate

Eligibility:

All Genders

Brief Summary

The aim of this quality control study is to compare two different techniques to determine ESBL-producing E.coli transmission.

Detailed Description

Pulse-field gel electrophoresis (PFGE) was considered the reference standard to determine transmission events of extended-spectrum Beta-Lactamase (ESBL) producing E.coli . However, this technique lack...

Eligibility Criteria

Inclusion

  • The patient population is defined as the 24 contact-index patient pairs identified during screening of contact patients after cessation of contact precautions as part of a quality control, performed from June 2012 to December 2013 at the University Hospital Basel and from January 2012 to December 2013 at the FELIX PLATTER-Hospital.

Exclusion

  • Patients not meeting the above mentioned inclusion criteria.

Key Trial Info

Start Date :

March 6 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

January 7 2025

Estimated Enrollment :

43 Patients enrolled

Trial Details

Trial ID

NCT04323553

Start Date

March 6 2020

End Date

January 7 2025

Last Update

January 15 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

University Hospital Basel, Division of Infectious Diseases and Hospital Epidemiology

Basel, Switzerland, 4031