Status:

UNKNOWN

Investigating the Specificity of Neural Correlates for Emotion Processing Deficits in Conduct Disorder and Autism Spectrum Disorders

Lead Sponsor:

University Hospital, Basel, Switzerland

Collaborating Sponsors:

Swiss National Science Foundation

Conditions:

Autism-Spectrum Disorder

Conduct Disorder

Eligibility:

All Genders

10-18 years

Brief Summary

This study is 1. to investigate the differential and shared neural underpinnings of facial emotion processing within Conduct disorder (CD) and Autism-Spectrum disorder (ASD) and 2. to investigate the...

Eligibility Criteria

Inclusion

  • For all participants: age between 10 and 18 years and an intelligence quotient score of 70 or higher.
  • For patient groups: confirmed clinical diagnoses according to Diagnostic and Statistical Manual (DSM)-5 of CD or ASD (depending on the group), without comorbid depression or anxiety psychological disorders.

Exclusion

  • For all participants: low intelligence (IQ\<70, as they might otherwise not fully understand what they are expected to do inside the scanner), insufficient German language skills or any contraindications for MRI (e.g. pregnancy, any non-removable metal within the subjects' body, claustrophobia).
  • For patient groups: severe developmental disorders, comorbid depressive and/or anxiety disorders will also be excluded from the study since it was shown that these patients might have problems in attention allocation under emotional stimulation.
  • For typically developing participants: suspicion of an undiagnosed clinical disorder

Key Trial Info

Start Date :

July 16 2020

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

June 1 2023

Estimated Enrollment :

120 Patients enrolled

Trial Details

Trial ID

NCT04324099

Start Date

July 16 2020

End Date

June 1 2023

Last Update

March 2 2022

Active Locations (1)

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Department of Child and Adolescent Psychiatry, KJPK (UPK)

Basel, Switzerland, 4002