Status:

COMPLETED

Developing Clinical Tools to Communicate Genetic Risk for Individuals Who Are Clinical High Risk for Psychosis

Lead Sponsor:

New York University

Collaborating Sponsors:

New York State Psychiatric Institute

Conditions:

Psychosis

Eligibility:

All Genders

16-30 years

Phase:

PHASE1

Brief Summary

While great strides are being made in identifying early signs that place people at a 'high risk state' for different illness conditions, at the same time, advances are being made in the identification...

Detailed Description

This project seeks to understand how individuals already in a high-risk state will interpret genetic information informing risk of 'conversion' to a full disorder. How individuals interpret this possi...

Eligibility Criteria

Inclusion

  • Male or females between the ages of 16- 30
  • Current or previous COPE participant
  • Identified as at clinical high risk for psychosis as defined as having at least one of the following: a)attenuated positive symptoms b)brief intermittent positive symptoms

Exclusion

  • Meeting CHR via only the Genetic risk and deterioration (GRD) syndrome. If the participant meets the GRD syndrome only, the investigators exclude the rare Genetic risk + deterioration (GRD) syndrome (comprising \<1% of CHR cases) because GRD requires having a 1st degree relative with any psychotic disorder, which may be linked with stronger reactions to genetic framings.
  • IQ \< 80
  • Inability to adopt hypothetical situation

Key Trial Info

Start Date :

November 16 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 31 2022

Estimated Enrollment :

25 Patients enrolled

Trial Details

Trial ID

NCT04325568

Start Date

November 16 2020

End Date

July 31 2022

Last Update

March 19 2024

Active Locations (1)

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Page 1 of 1 (1 locations)

1

New York State Psychiatric Institute

New York, New York, United States, 10032