Status:
COMPLETED
Role of Dexamethasone in Multimodal Analgesia for Postoperative Pain in Thoracic Surgery
Lead Sponsor:
University of Trieste
Conditions:
Dexamethasone Adverse Reaction
Postoperative Pain
Eligibility:
All Genders
18+ years
Brief Summary
The aim of the study is to evaluate the analgesic properties of dexamethasone and to quantify the possible associated postoperative complications, such as wound infections and hyperglycaemia, in patie...
Detailed Description
We designed an observational study, aimed to evaluate the possible reduction in morphine consumption in thoracic patients, who were administered dexamethasone compared to who didn't received the drug....
Eligibility Criteria
Inclusion
- BMI \< 30 kg/m2
- ASA I-III
- Lobectomy, segmentectomy or atypical resection surgery with a mini-thoracotomy approach or VATS
Exclusion
- Refusal by the patient to participate or patient unable to express his own consent
- Chronic therapy with medium-high doses of corticosteroids
- Chronic therapy with opioids
- METS ≤ 4, defining an overall decreased cardiovascular fitness
- Urgent or emergency surgery
- Allergy to the active ingredient of the drug used
- Kidney failure at stage III or more
- Liver failure
- Pregnancy
- Drug addiction, patients with a history of drug abuse
- Corrected Qt interval (QTc) \> 0,45 for males and 0,47 for women
Key Trial Info
Start Date :
August 29 2017
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 6 2019
Estimated Enrollment :
62 Patients enrolled
Trial Details
Trial ID
NCT04325984
Start Date
August 29 2017
End Date
March 6 2019
Last Update
March 30 2020
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Cattinara Hospital
Trieste, Italy, 34149