Status:
COMPLETED
Optical Coherence Tomography Angiography Evaluation of Ocular Changes in Patients With Carotid Artery Stenosis
Lead Sponsor:
First Affiliated Hospital of Harbin Medical University
Conditions:
Carotid Stenosis
Eligibility:
All Genders
18-100 years
Brief Summary
This study aims to evaluate ocular changes in patients with carotid artery stenosis by optical coherence tomography angiography before and after carotid artery revascularization procedure.
Detailed Description
A growing body of research indicates that abnormal ocular microvascular features may serve as a novel biomarker reflecting the severity of underlying cardiovascular, neurodegenerative, and microvascul...
Eligibility Criteria
Inclusion
- Clinical diagnosis of carotid artery stenosis
- Age-gender-race-matched controls
Exclusion
- age \<18 years
- intraocular pressure (IOP) \>21 mmHg
- VA \>logMAR 1.0
- spherical equivalent (SE) between \>1.00 or \< -6.00 D
- other serious eye diseases which may affect OCTA results including diabetic retinopathy, hypertensive retinopathy, retinal vascular occlusion, age-related macular degeneration, and uveitis
- major intraocular surgery performed in the past 6 months or a history of laser photocoagulation or intravitreal injection
- glaucoma or first-degree relatives with a history of glaucoma; and
- any disease that might cause poor scan quality (image quality \<6).
Key Trial Info
Start Date :
April 2 2020
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 2 2020
Estimated Enrollment :
129 Patients enrolled
Trial Details
Trial ID
NCT04326842
Start Date
April 2 2020
End Date
July 2 2020
Last Update
October 19 2020
Active Locations (1)
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1
The First Affiliated Hospital of Harbin Medical University
Harbin, Heilongjiang, China