Status:

COMPLETED

Use of Blood Biomarkers to Predict Gastric Cancer Risk

Lead Sponsor:

National University Hospital, Singapore

Collaborating Sponsors:

Tan Tock Seng Hospital

MiRXES Pte Ltd

Conditions:

Stomach Neoplasm

Eligibility:

All Genders

40+ years

Brief Summary

This study aims to develop a cost-effective screening strategy for the Singapore population by targeted screening of people who have a high risk of stomach cancer, in order to detect early signs of th...

Detailed Description

Objectives: This study aims to 1. Validate the predictive value of various blood biomarkers, including the panel of antibodies against H.pylori and pepsinogen levels, micro RNAs (miRNAs) and blood-b...

Eligibility Criteria

Inclusion

  • The subject is greater than 40 years of age.
  • The subject is scheduled to undergo an endoscopy because of medical indication.
  • The subject must have personally signed and dated the patient informed consent form indicating that he/she has been informed of all pertinent aspects of the study.
  • The subject must be willing and able to comply with all study procedures.

Exclusion

  • The subject who is unable to undergo gastroscopy.
  • The subject with previous total or partial gastrectomy.
  • The subject has other severe acute or chronic medical or psychiatric condition or laboratory abnormality that may interfere with the interpretation of study results and in the judgment of the investigator would make the subject unsuitable for entry into the study.
  • The subject is unwilling or unable to provide signed informed consent.
  • The subject who is pregnant.

Key Trial Info

Start Date :

December 3 2012

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

May 29 2016

Estimated Enrollment :

6862 Patients enrolled

Trial Details

Trial ID

NCT04329299

Start Date

December 3 2012

End Date

May 29 2016

Last Update

October 22 2020

Active Locations (2)

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Page 1 of 1 (2 locations)

1

National University Hospital, Singapore

Singapore, Singapore, 119074

2

Tan Tock Seng Hospital, Singapore

Singapore, Singapore, 308433