Status:
COMPLETED
Implementation of an Integrated Care Strategy for Children Contacts of Patients With Tuberculosis
Lead Sponsor:
Corporacion para Investigaciones Biologicas
Collaborating Sponsors:
Universidad Pontificia Bolivariana
Universidad de Antioquia
Conditions:
Latent Tuberculosis
Eligibility:
All Genders
Up to 5 years
Brief Summary
Introduction: childhood tuberculosis continues to be a major public health problem, despite the fact that the visibility of the epidemic in this population group has increased, studies are still lacki...
Detailed Description
Objective: To design, implement and evaluate an integrated care strategy for children under five years old household contacts of patients with smear positive pulmonary tuberculosis in Medellín and th...
Eligibility Criteria
Inclusion
- Inclusion criteria for initial evaluation (clinical and paraclinical)
- Child under five years of age.
- Household contact of smear positive confirmed pulmonary tuberculosis patient.
- That the parents or legal guardian sign the informed consent.
- To live in Medellín or the Metropolitan Area of the Aburrá Valley.
- Diagnostic criteria for latent tuberculosis
- Asymptomatic child.
- Normal clinical assessment, without clinical signs of active TB.
- Normal chest x-ray.
- Response to the tuberculin skin test (TST) ≥5 mm and / IGRA (QuantiFERON®-TB Gold Plus - QFT Plus) positive.
- Inclusion criteria to start treatment for latent tuberculosis infection
- Having a diagnosis of latent tuberculosis or
- Being in immunological window period.
Exclusion
- Exclusion criteria for receiving treatment for latent tuberculosis
- Having symptoms or signs of active TB and that the disease has not been ruled out.
- Having basic liver disorder.
- Exclusion criteria for performing induced sputum
- • Having severe asthma.
Key Trial Info
Start Date :
July 26 2021
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 31 2023
Estimated Enrollment :
163 Patients enrolled
Trial Details
Trial ID
NCT04331262
Start Date
July 26 2021
End Date
July 31 2023
Last Update
August 30 2023
Active Locations (1)
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1
Corporación para Investigaciones Biológicas
Medellín, Colombia