Status:
UNKNOWN
Cryptosporidium Infection and Human Colorectal Cancer
Lead Sponsor:
Lille Catholic University
Collaborating Sponsors:
Institut Pasteur de Lille
Conditions:
Colonic Neoplasms
Cryptosporidiosis
Eligibility:
All Genders
18+ years
Brief Summary
It has been reported that Cryptosporidium parvum, a species of a protozoan frequently isolated from humans and animals, is able to induce digestive adenocarcinoma in a rodent model. Consistently, some...
Eligibility Criteria
Inclusion
- Cases:
- Age ≥ 18 years old
- Patients with colonic adenocarcinoma/intraepithelial neoplasia diagnosed prior to chemotherapy or radiotherapy who will undergo scheduled surgery. Patients with rectal cancer with indication for neoadjuvant treatment will still be included, but only biopsies used for diagnosis will be used
- Patient capable of receiving informed information
- Written informed consent
- Affiliation to a social security scheme
- Controls:
- Age ≥ 18 years old
- Patients with endoscopic indication for benign pathology
- Patients with indication for colectomy for benign pathology
- Patients with digestive cancer (stomach, oesophagus, biliary, pancreatic, etc.) of any type other than colorectal cancer before chemotherapy or radiotherapy
- Patient capable of receiving informed information
- Written informed consent
- Affiliation to a social security scheme
Exclusion
- Patients undergoing pre-operative chemotherapy.
- Patients who have already had chemotherapy for less than one year or other immunosuppressive treatment
Key Trial Info
Start Date :
June 30 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 30 2024
Estimated Enrollment :
324 Patients enrolled
Trial Details
Trial ID
NCT04332705
Start Date
June 30 2020
End Date
December 30 2024
Last Update
November 18 2023
Active Locations (1)
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1
Groupement des Hôpitaux de l'Institut Catholique de Lille
Lomme, Nord, France, 59462