Status:

COMPLETED

Endovascular Therapy for Erectile Dysfunction

Lead Sponsor:

Clinica San Gaudenzio

Conditions:

Erectile Dysfunction

Eligibility:

MALE

18+ years

Brief Summary

Brief Summary: Background and pathophysiology Erectile dysfunction is a serious disease with a significant impact on the quality of life. Male erection is a complex mechanism that involves neuro-vascu...

Detailed Description

Detailed Description: The objective of this study is to evaluate of the safety and feasibility of endovascular therapies in segmental atherosclerotic lesions of the internal pudendal arteries among me...

Eligibility Criteria

Inclusion

  • Age \> 18 years old
  • Be able to understand and sign a witnessed informed consent for the procedure
  • Eligibility for percutaneous peripheral intervention
  • Baseline IIEF-5 score evaluation \< 15
  • PSV \< 25 cm/sec
  • Stable hemodynamic conditions
  • Normal ejection fraction
  • Being refractory to oral PDE5-I for at least 6 months before enrollement
  • Treatable angiographic lesions of the pudendal arteries

Exclusion

  • Heart failure
  • Hemodynamic instability
  • Basal IIEF-5 and doppler examination
  • Blood count not within normal ranges
  • No history of bleeding or coagulopathy
  • No other serious medical illness
  • Other investigational drug or device study
  • Pudendal artery \< 1.5 mm and lesion lenght greater than 80 mm by visual estimation
  • Pudendal restenosis from previous intervention

Key Trial Info

Start Date :

February 1 2017

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

January 1 2020

Estimated Enrollment :

300 Patients enrolled

Trial Details

Trial ID

NCT04333173

Start Date

February 1 2017

End Date

January 1 2020

Last Update

April 3 2020

Active Locations (1)

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1

Centro Cuore

Novara, Italy