Status:
UNKNOWN
Lactoferrin in Treatment of Fe Deficient Anemia In Cirrhosis
Lead Sponsor:
Post Graduate Institute of Medical Education and Research, Chandigarh
Conditions:
Iron Deficiency Anemia
Chronic Liver Failure
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
Iron deficiency and altered homeostasis due to inflammation and decreased iron utilization are main factors involved in anemia in liver disease. Lactoferrin is a first line defence protein for protect...
Detailed Description
Lactoferrin is a highly conserved, monomeric 80 kDa single polypeptide chain contained in most mammalian exocrine secretions, such as milk, saliva and tears, bronchial, and intestinal secretions. LTF ...
Eligibility Criteria
Inclusion
- Age 18-75 years
- Either gender
- Patients with chronic liver disease with iron deficiency anemia with transferrin saturation\<20% and Hemoglobin in Non-pregnant women (15 years of age and above) \<12g/dl and in men \<13g/dl -
Exclusion
- Those who do not consent to participate in the study
- Inability to obtain informed consent from patient or relatives
- Severe preexisting cardiopulmonary disease
- Renal dysfunction (S. Creatinine ≥ 2mg/dL)
- Pregnancy/Lactation
- Post liver transplant patients
- HIV infection
- Patients who are on psychoactive drugs, like sedatives or antidepressants
- Patients who are too sick to carry out the protocol
Key Trial Info
Start Date :
January 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2023
Estimated Enrollment :
130 Patients enrolled
Trial Details
Trial ID
NCT04335058
Start Date
January 1 2020
End Date
December 1 2023
Last Update
May 1 2023
Active Locations (1)
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1
Postgraduate Institute of Medical Education and Research
Chandigarh, India, 160012