Status:

COMPLETED

Dose-Finding of Lower Limb Mirror Therapy After Stroke.

Lead Sponsor:

University of East Anglia

Conditions:

Stroke

Eligibility:

All Genders

18+ years

Phase:

EARLY_PHASE1

Brief Summary

This study will investigate the maximum dose per day of using mirror therapy for ankle exercise after stroke. The design is a 3+3 rule based, dose- finding study. Each cohort will consist of three par...

Detailed Description

Procedure:a 3+3 rule-based, dose-escalation design (Colucci et al,2017). recruitment process: the study will begin with a cohort of three participants (n=3). Each of the subsequent cohorts will also b...

Eligibility Criteria

Inclusion

  • Participants have had a stroke for six weeks or more before recruitment to this study, and are discharged from NHS statutory stroke rehabilitation.
  • Participants will be at least 18 years of age
  • Able to produce some voluntary contraction of paretic ankle ( motricity index between 9 and 19).
  • Ability to understand and follow simple verbal instructions (one-stage commands), i.e. sufficient communication, orientation, and memory to participate in mirror therapy ankle exercise.
  • Participants will have had no lower limb injury in the last six months and were able to walk independently indoors before the index stroke.

Exclusion

  • Foot or ankle contracture that prevents 50% of the passive range of motion.
  • Any condition that can be exaggerated by performing the therapy.

Key Trial Info

Start Date :

April 23 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 9 2021

Estimated Enrollment :

19 Patients enrolled

Trial Details

Trial ID

NCT04339803

Start Date

April 23 2019

End Date

August 9 2021

Last Update

November 8 2021

Active Locations (1)

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1

Sarah Bajuaifer

Norwich, United Kingdom, NR4 7TJ