Status:
COMPLETED
Brain Effects of Opiate Agonist and Antagonist
Lead Sponsor:
University of Rochester
Conditions:
Chronic Low-back Pain
Eligibility:
All Genders
18-65 years
Phase:
PHASE4
Brief Summary
This study will look at the short-term effect of morphine on brain response to food.
Detailed Description
Chronic low back pain patients and healthy controls will be recruited for this study. Participants' brain will be scanned at baseline and then again on a different day after the administration of an o...
Eligibility Criteria
Inclusion
- Healthy participants
- Patients in pain: suffering from persistent pain more days than not, 3/10 in intensity on a numerical rating scale, for at least 6 weeks or more.
Exclusion
- Any DSM diagnosis
- diabetes
- food allergies
- lactose intolerance
- participants seeking to quit smoking or to lose weight
- participants on any psychotropic medication including opiate based analgesics (e.g. oxycodone, methadone, suboxone)
- pregnant or nursing women
- pacemaker or other implanted electrical devices
- Participants with a past history of head trauma or seizures
- Any past history of illegal drug or alcohol misuse
- Participants who cannot undergo an MRI scan.
Key Trial Info
Start Date :
April 27 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 16 2019
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT04342130
Start Date
April 27 2018
End Date
April 16 2019
Last Update
May 7 2021
Active Locations (1)
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1
Yale University
New Haven, Connecticut, United States, 06519