Status:

COMPLETED

Oocyte Survival After Vitrification With Slush Nitrogen Compared With Liquid Nitrogen

Lead Sponsor:

Reproductive Medicine Associates of New Jersey

Conditions:

Infertility

Eligibility:

FEMALE

18-30 years

Phase:

NA

Brief Summary

The purpose of this study is to determine if the use of slush nitrogen results in higher post-thaw survival rates for oocytes compared to conventionally used liquid nitrogen.

Detailed Description

The study is a randomized, controlled trial which seeks to characterize oocyte survival rate following vitrification and subsequent warming with both slush nitrogen and liquid nitrogen. After warming,...

Eligibility Criteria

Inclusion

  • Major Inclusion Criteria for oocyte donors:
  • Age 30 years or younger who meet institutional criteria to be an oocyte donor.
  • Patients who agree to donate oocytes for research purposes and agree to the study protocol.
  • The subgroup of oocyte donors age 35-38 will not be part of the primary analysis, and therefore will not be required to meet the age criteria listed above. The older group of donors will be chosen as the clinical discretion of the study investigators. No specific ovarian reserve cutoffs will be required, although factors related to ovarian reserve will be taken into consideration.
  • Major Exclusion Criteria for oocyte donors:
  • Under 18 years old
  • All patients who do not voluntarily give their written consent for participation.
  • Patients who do not meet standard institutional criteria for oocyte donation.
  • A diagnosis of polycystic ovarian syndrome (PCOS).

Exclusion

    Key Trial Info

    Start Date :

    April 8 2020

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    July 1 2021

    Estimated Enrollment :

    27 Patients enrolled

    Trial Details

    Trial ID

    NCT04342364

    Start Date

    April 8 2020

    End Date

    July 1 2021

    Last Update

    January 14 2022

    Active Locations (1)

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    Reproductive Medicine Associates of New Jersey

    Basking Ridge, New Jersey, United States, 07920