Status:

COMPLETED

Probiotics for Treatment of Chalazion in Adults

Lead Sponsor:

University of Molise

Conditions:

Chalazion

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

There is growing evidence encouraging probiotics use in several diseases. The aim of the investigator's study is to define the possible beneficial impact of probiotics on adults suffering from chalazi...

Detailed Description

Prospective comparative pilot study on 20 adults suffering from chalazion randomly divided into two groups. The first group, received conservative treatment with lid hygiene, warm compression, and dex...

Eligibility Criteria

Inclusion

  • history of rapid onset of painful inflamed mass that had reached a stationary size for more than 2 months
  • clinical appearance and location of the lesion

Exclusion

  • eyelid infection
  • chalazion duration \< 1 month
  • nonpalpable chalazion
  • suspicion of malignancy
  • comorbidities (constitutional atopy and seborrheic dermatitis, hormonal dysfunction, presence of irritable bowel disease, infectious mainly related to Staphylococcus aureus and Propionibacterium acnes, demodex mite infestation, vitamin A deficiency, arterial hypertension, diabetes and pregnancy)
  • personal habits (smoking, eating disorders, etc.)

Key Trial Info

Start Date :

February 1 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 29 2020

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT04342507

Start Date

February 1 2019

End Date

February 29 2020

Last Update

April 14 2020

Active Locations (1)

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1

University of Molise

Campobasso, Molise, Italy, 86100